And from way out of left field, one of fantasy football’s most dependable quarterbacks is in jeopardy of missing the first regular season game of his career due to injury. According to reports, Purdy began to experience symptoms on the team’s flight back to San Francisco after their Monday night loss to the Vikings. In line to start if he isn’t cleared by the end of the week would be QB Sam Darnold, who beat out former 49ers 3rd overall pick Trey Lance for the No. 2 job this past training camp. Darnold would certainly be worth a look off the waiver wire for teams in need at QB, but he isn’t a priority addition given that there are no teams on bye and the fact that he may only need to step in this week. San Francisco’s skill players - Brandon Aiyuk, George Kittle, and CMC - shouldn’t be downgraded much, if at all, as a result of Purdy’s concussion, although their floors and ceilings may be a bit lower than usual.