With no answers over the past week about Cooper Kupp’s status for Week 1, it’s probably best to head into Week 1 as if he’s already been ruled out for this weekend. While there’s still a slight chance that Kupp could be ready to play by Week 1, it’s unlikely that he’d be able to recover from a setback to his hamstring injury in such short order. At this point, it wouldn’t be surprising to see the Rams hold Kupp out to begin the year to allow him to come back at full strength as soon as possible. The Chargers faced a similar dilemma last season with Keenan Allen, whom they rushed back into action and saw miss additional games as a result. Fantasy managers should turn to the waiver wire to scoop up Van Jefferson and even Puka Nacua in Kupp’s abscence, but neither of them will come remotely close to filling the hole left by him in fantasy lineups.